Doctor: I picked up attributes in the hospital

Chapter 302 Mitefuxing?New Hope for Healing!

Chapter 302 Mitefuxing?New Hope for Healing!

"Xiao Zhao, how is the patient's current condition?"

As soon as Zhao Heng sat down, the dean Liu Shangming couldn't help asking. Originally, he also wanted to call Zhao Heng over to ask about the patient's condition.

Right after the minimally invasive material collection operation was over and the infection was diagnosed, he immediately reported the infection case to the ministry, which also took it very seriously, and immediately set up a working group to deal with this public emergency event.

However, despite the attention of the Ministry, it is not easy for Liu Shangming. After all, it is a "brain-eating amoeba". It can be said that it is notorious in the field of infectious diseases. For such a deadly parasite The treatment of infection is the biggest problem at present.

"The patient's vital signs were relatively stable, but there was very intense activity in the cerebral cortex."

Zhao Heng reported.

"Strong activity in the cerebral cortex? This means that the reproduction of the parasitic worms in the patient's brain has reached its peak."

Hearing Zhao Heng's report on the infected patients, Liu Shangming, who has rich experience and knowledge, immediately realized that the parasites in the patient's brain had entered the peak period of reproduction.

If there is no good way to suppress the reproduction of parasites in the patient's brain, then as the parasites multiply in the next step, the patient's cerebral edema will further aggravate, which is a process of death step by step.

"What is the current treatment plan for the patient?"

Liu Shangming asked again.

"A combination of dehydrating agent and nimodipine was used, and mild hypothermia treatment was performed on the patient. In terms of antibiotics, a combination of amphotericin B was used."

Zhao Heng mentioned the current treatment plan.

"This treatment plan is already perfect, and it is already the best that can be done under the current circumstances, but just like this, it still cannot suppress the reproduction of parasites in the patient's brain. This time, the situation is more complicated."

Dean Liu Shangming thought for a while and said.

Gao Jun and Zhao Heng here can be said to be their own people, so the dean Liu Shangming speaks very directly, and there is nothing to hide.

"Xiao Zhao, you just do your best. There are currently 10 cases reported in the country that have been infected with Fuxella worm. All of these 10 infected patients died without exception, so don't put too much pressure on you."

Gao Junsheng was afraid that Zhao Heng would be under too much pressure, so he said to him.

Doctors are not omnipotent. In this world, there are still many diseases that modern medicine cannot cure, and even the pathogenesis has not been clarified.

Therefore, when faced with these incurable diseases, it is a test of the doctor's psychological quality.

In Gao Jun's view, geniuses like Zhao Heng, in particular, are more likely to be influenced, and even cause psychological shadows to a certain extent, affecting his future career.

Hearing Gao Jun's words, Liu Shangming also nodded slightly. In some cases, humans cannot do it. Doctors are not gods, and they are not omnipotent.

What's more, for the occurrence of various possible situations, the hospital also needs to make plans.

"Principal, teacher, I have a discovery about the treatment of this patient infected with Fueri worm."

Zhao Heng saw that the dean Liu Shangming and the teacher Gao Jun were both thinking about themselves, and felt warm in his heart. He thought about it and said.

The teacher loves and cares about the students and subordinates, so as a student, he naturally has to do his best.

"Well, you talk about it."

Dean Liu Shangming's eyes lit up when he heard Zhao Heng's words. During this period of time, he was most concerned about Zhao Heng for young doctors.

Zhao Heng, a young doctor, always surprises people. It seems that miracles often happen to him. This is an incredible thing for a young doctor.

"Dean, I saw a case, which was a foreign case infected with Fueri worm, and survived after treatment. I found that this patient had early onset skin cancer, so the attending doctor has been using rice for him. Fu Xing, after the diagnosis of Boudella infection, the doctor discovered that miltefucin seems to have a certain effect on the treatment of Boudella infection, and the patient was in the early stage of infection, so this became one of the few cured cases."

Zhao Heng organized the language and said.

"Miltefosin? As an alkylphosphocholine drug, miltefosin does have certain activity against various parasites. Among them, the main mechanism of action is to inhibit the PI3K/Akt survival pathway in patients. It can also inhibit the release of anti-Ige-induced histamine from human skin mast cells, reduce the cytokines IL-1β, IL-4 and IL-6 in skin tissue cells, and strongly inhibit the esterification of cholesterol. "

When it comes to anti-cancer drugs, as the director of the oncology department and the absolute authority on cancer treatment in China, Liu Shangming is very familiar with it, and the ones he is familiar with cannot be more familiar.

"This is a good attempt. At present, we are not the only ones treating patients infected with Fueri worm. I got news that there have been no less than 10 cases of infection in country H, and the treatment effect is not very satisfactory. "

Gao Jun also nodded and said.

Zhao Heng has never let him down. Maybe someone can rival Zhao Heng in terms of knowledge and professionalism, but in terms of clinical thinking, Zhao Heng can be said to be the most open-minded person Gao Jun has ever met.

Broad clinical thinking is extremely important for a doctor.

"Xiao Zhao, tell me more about what you think."

Liu Shangming thought about it and said to Zhao Heng.

When Zhao Heng said Mi Tifu Xing, a treatment plan appeared in his mind, but he still wanted to hear Zhao Heng's thoughts, which was also giving young people a chance.

If Zhao Heng hadn't mentioned miltefucin, he would never have thought of a drug that can treat cancer, and it can also be used to treat Fucheni infection.

"Dean, the molecular weight of miltefucin is 407.57, which is a small molecular substance, so I think that on the basis of traditional drug delivery, nanometer drug delivery can be applied, so that the effect will be faster. Patients now The situation is critical, and the faster the effect, the higher the chance of survival."

Zhao Heng thought about it for a while and said, when he saw that mitifusin might be effective against Fudei infection, Zhao Heng thought of the nanotherapy project researched by Professor Li Hongwei from the School of Life Sciences of Yanjing University.

This nanotherapy, to put it simply, is to use nanoparticles to improve the bioavailability of therapeutic drugs and delay drug metabolic activity.

For example, carbon nanotubes, polymer nanoparticles, nanodendrites, etc., can use nanoparticles or nanomaterials with unique properties to improve the pharmacokinetic characteristics of drug molecules and form new drug delivery based on nanomedicine. system.

Moreover, in terms of nano-therapy, Professor Li Hongwei from the School of Life Sciences of Yenching University has already come to the forefront in this regard.

(End of this chapter)